产品货号：
GS4445
中文名称：
重组人EMAP-II
英文名称：
Recombinant Human Endothelial-Monocyte Activating Polypeptide II
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 18.2kDa,a single non-glycosylated polypeptide chain containing 166 amino acids.
储存条件：冷冻（-20℃）
概述
Endothelial-Monocyte Activating Polypeptide II(EMAP-II)is a tumor derived cytokine that exerts a wide range of activities on endothelial cells,monocytes and neutrophils.EMAP-II inhibits endothelial cell proliferation,vasculogenesis,neovessel formation,and can induce apoptosis.It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils.Of clinical importance,EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.Mature EMAP-II is an 18.3 kDa protein,which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人EMAP-II，EMAP-II, Human
储存条件：冷冻（-20℃）
概述
Endothelial-Monocyte Activating Polypeptide II(EMAP-II)is a tumor derived cytokine that exerts a wide range of activities on endothelial cells,monocytes and neutrophils.EMAP-II inhibits endothelial cell proliferation,vasculogenesis,neovessel formation,and can induce apoptosis.It is also chemotactic towards neutrophils and monocytes and induces myeloperoxidase activity from neutrophils.Of clinical importance,EMAP-II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.Mature EMAP-II is an 18.3 kDa protein,which is synthesized as the C-terminal portion of a biologically inactive precursor protein containing a propeptide of 146 amino acid residues.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞98%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by the apoptotic effect using serum free human MCF-7 cells is less than 40ng/ml,corresponding to a specific activity of>2.5×104 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rHuEMAP-II as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SKPIDVSRLD LRIGCIITAR KHPDADSLYV EEVDVGEIAP RTVVSGLVNH VPLEQMQNRM VILLCNLKPA KMRGVLSQAM VMCASSPEKI EILAPPNGSV PGDRITFDAF PGEPDKELNP KKKIWEQIQP DLHTNDECVA TYKGVPFEVK GKGVCRAQTM SNSGIK |
相关搜索：重组人EMAP-II，EMAP-II, Human